Title
ENANTIOSPECIFIC REDUCTION OF AROMATIC KETONES IN A GREMMENIELLA ABIETINA CULTURE
Autor
Ewa Brzezowska, Jadwiga Dmochowska-Gładysz, Bogdan Jarosz, Tadeusz Kowalski
Keywords
Gremmeniella abietina, biotransformation, enantiospecificity, ketone reduction
Abstract
A Gremmeniella abietina strain, a Scots pine pathogenic fungus, was used to investigate its ability to reduce five selected acetophenones, aromatic prochiral ketones. In all cases enantiospecificity of the process was recorded, and the enantiospecificity, calculated as the enantiomeric excess, as well as resulting secondary alcohol yield, depended on the reaction time and the structure of a given substrate.
Pages
105-110
Cite
Brzezowska, E., Dmochowska-Gładysz, J., Jarosz, B., Kowalski, T. (2006). ENANTIOSPECIFIC REDUCTION OF AROMATIC KETONES IN A GREMMENIELLA ABIETINA CULTURE. Acta Sci. Pol. Biotechnol., 5(1-2), 105-110.
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