The influence of infection of Trichinella pseudospiralis on the eosinophiles, plasma cells, mast cells, lymphocytes T CD4, lymphocytes B and macrophages in the jejunum were studied. The mice divided into two group: control and experimental. The mice of other group were infected per os with 200 Trichinella pseudospiralis. The mice were killed between the 7 – 175 th d.p.i., after which histological preparations were made from the jejunum. The examinations were made using immunofluorescent and immunoenzymatic methods with monoclonal antibody. Suppression of CD4 lymphocytes, B lymphocytes, plasma cells and macrophages was observed in the jejunum of mice infected Trichinella pseudospiralis than in the control mice. During the examinations in experimental group of animals was observed high level of eosinophiles and mast cells.

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