The aim of the study was to investigate the effect of L-alanyl–L–glutamine (Ala-Gln) on the femur structure, geometric and mechanical properties and mineralization in piglets at 8^th week of age. The studies were carried out on 23 piglets between the 1^st and the 56^th day of life. Piglets received orally either 0,4g/kg b. wt. of Ala-Gln solution (Ala-Gln group) or 2 ml/kg b.wt. of saline (control). The piglets were sacrificed at the 56^th days of life and bones were stripped out for further analyses. Bone mineral density in the proximal and distal epiphysis as well as physical parameters (Break strength, maximum elastic force) and geometrical properties (cross sectional area, second moment of inertia, mean relative wall thickness) were analyzed. In histological pictures trabeculae area, length and density in the femoral epiphysis and metaphysis were measured. Physical, geometrical and morphometrical parameters of the femur tendent to increase in Ala-Gln treated piglets. In conclusion, oral administration of Ala-Gln during 8 weeks of life positively affected the development of the femur in piglets.

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