The strain of Absidia coerulea 93 was used to investigate the transformations of C₁₈ steroids: 19-nortestosterone and its 17α-alkyl and ethynyl derivatives. 19-nortestosterone and its 17α-alkyl derivatives were transformed, forming hydroxylated products. It was found that the position of the introduced hydroxyl group depended on the structure of the substrate: 19-nortestosterone underwent hydroxylation at C15, whereas 19-nortestosterone 17α-alkyl derivatives were predominantly hydroxylated at 7α-position. Besides hydroxylation introduction of double bond C6-C7 was observed. It was noticed that 19-nortestosterone 17α-ethynyl derivatives were not transformed in Absidia coerulea culture.

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