In 2006-2008 strict, one-factorial field experiments were established in randomized block design with the control in four replications at three fields situated in Kurowo (52^o07’ N; 16^o39’ E), Czerniejewo (52^o26’ N; 17^o29’ E) and Winna Góra (52^o12’ N; 17^o27’ E). The main goal of the presented paper was to evaluate the selected herbicide selectivity and effectiveness in cultivation of the sorghum cultivar Sucrosorgo 506. Sorghum is considered a minor crop in Poland. There are no registered herbicides, so it is necessary to provide management options for weed control in sorghum. The following active ingredients were tested: s-metolachlor (Dual Gold 960 EC 1.5 dm³·ha^-1), acetochlor (Trophy 786 EC 2.5 dm³·ha^-1), dicamba (Banvel 480 SL 0.5 dm³·ha^-1), florasulam + 2,4D (Mustang 306 SE 0.6 dm³·ha^-1), fluoroksypyr + 2,4D (Aminopielik Gold 530 EW 1.25 dm³·ha^-1), mesotrione (Callisto 100 SC 1.5 dm³·ha^-1), MCPA (Chwastox Extra 300 SL 3.0 dm³·ha^-1), MCPA + dicamba (Chwastox Turbo 340 SL 2.0 dm³·ha^-1), foramsulfuron + iodosulfuron methyl sodium (MaisTer 310 WG 0.15 kg·ha^-1). Dual Gold 960 EC and Trophy 768 EC were applied directly after crop sowing and the other herbicides at the 3-4 leaf stage of sorghum. Weed control effectiveness was assessed 3-4 weeks after herbicide application. Before harvesting, the fresh weight of five sorghum plants and plant density were determined. The research indicated that years of experiments significantly influenced the herbicides selectivity. Fresh weight of 5 sorghum plants was significantly higher in comparison with the control plants after Trophy 786 EC (in 2006) and Chwastox Turbo 340 SL (in 2008) application, while sorghum density was influenced by Chwastox Turbo 340 SL (in 2006 and 2007) and Banvel 480 SL (in 2007). Maister 310 WG applied with adjuvant Actirob 842 EC caused the total destruction of sorghum.

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