The objective of this study was comparative histological evaluation of healing of intestinal anastomoses in pigs operated on with different methods, i.e. mechanical and manual anastomoses. We decided to trace the process of healing of the intestinal wall anastomosed with biofragmentable anastomosis ring (BAR, Valtrac), round stapler (ILS 25) and manually placed nonabsorbable polyester sutures (Mersilene). The healing of the anastomoses was evaluated histologically in 21 pigs, on the 14^th, 30^th and 90^th day after the operation. The healing of anastomoses made with different techniques and materials was evaluated based on the score of overall intensity of inflammatory reaction proposed by Sewell and Deveney. It was found that the inflammatory reaction in the intestinal wall was least pronounced after the use of BAR. The anastomoses made with polyester sutures and steel staples produced more intensive inflammation in the first phase, due to the presence of a foreign body.

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