Acta Scientiarum Polonorum

Scientific paper founded in 2001 year by Polish agricultural universities

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Administratio Locorum
(Gospodarka Przestrzenna) 10 (4) 2011     ISSN: 1644-0741
Title
EXPERIMENTAL METHODS OF ABDOMINAL AORTIC ANEURYSM CREATION WITH PARTICULAR EMPHASIS ON SWINE AS A LARGE ANIMAL MODEL
Autor
Albert Czerski, Jolanta Bujok, Agnieszka Rusiecka, Wojciech Zawadzki, Jan Gnus, Willy Hauser, Kornel Ratajczak, Wojciech Witkiewicz
Keywords
abdominal aortic aneurysm (AAA), large animal model, swine, aneurysm creation
Abstract
Abdominal aortic aneurysm (AAA) is on the 10th position of the causes of death in men above 55 years of age. Method of treatment of AAA measuring above 5,5 cm is the classical surgery or endovascular procedure. Death and complication rates associated with surgery are still high. For this reason further studies on pathogenesis, pathophysiology and treatment of abdominal aortic aneurysm are needed. Numerous animal models of AAA have been developed. Research is conducted on predisposed animals and on models, in which AAA have been induced by chemical or physical methods. Swine are good experimental model for the improvement of new surgical techniques. Many physical protocols are used to produce aneurysm in swine (especially operational), combinations of physical and chemical methods are also introduced and constantly improved.
Pages
5-22
Cite
Czerski, A., Bujok, J., Rusiecka, A., Zawadzki, W., Gnus, J., Hauser, W., Ratajczak, K., Witkiewicz, W. (2011). EXPERIMENTAL METHODS OF ABDOMINAL AORTIC ANEURYSM CREATION WITH PARTICULAR EMPHASIS ON SWINE AS A LARGE ANIMAL MODEL. Acta Sci. Pol. Med. Vet., 10(4), 5-22.
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