The production of citric acid from glucose syrup by acetate mutant strain of Y. lipolytica K-1 in the membrane reactor with using continuous yeasts recycling by microfliltration module was examined. Citrate production rates and yields achieved in the Continuous Membrane Stirred Tank Reactor were dependent on composition of the feed medium. Experiments in CMSTR have shown that presence of yeast extract in the feed medium (0,2 gL^-1) is the most suitable for both citric acid production and stability of the continuous process with smooth strain of K-1. The volumetric citric acid production rate (Q_CA) obtained in CMSTR with high biomass concentration ranged from 1,1 to 1,2 gL^-1h^-1.

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