The studies were executed in aim of determining of an ethanol extract of propolis (EEP) influence, which was administered to calves with diarrhoea symptoms. The research were executed on 40 calves of Holstein-Friesian race, beginning from 7 days of their life, divided on 5 groups. Through period of 1 or 2 weeks, the calves were fed with different doses (2 or 4 ml) of EEP alongside with milk. The estimation of influence of applied preparation was based on clinical observation, bacteriological examination of faeces, hematological blood parameters as well as on marking of total protein and its fraction. The research were showed that EEP supplement, which was applied to calves with diarrhoea, caused an improvement of calves wholesome and appeasement and inhibition of diarrhoea symptoms. The EEP also caused considerable reduction of microorganisms number in faeces, from 42,93 to 77,46% (in this E. coli from 27,69 to 77,83%), what was depended on quantity and duration of administering of EEP. The advantageous effect of propolis on hematological blood parameters as well as total protein levels and gamma globulins in blood serum was affirmed. At calves receiving EEP, higher circadian growths of body weight in comparison to control group was affirmed.

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