Acta Scientiarum Polonorum

Scientific paper founded in 2001 year by Polish agricultural universities

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Biotechnologia
(Biotechnologia) 17 (2) 2018
Title
INVESTIGATION OF CYTOTOXICITY OF OXYGEN NANOBUBBLE DISPERSIONS
Autor
Karol Ulatowski, Paweł Sobieszuk, Aleksandra Kuźmińska, Tomasz Ciach
Keywords
nanodispersion, MTT test, cytotoxicity
Abstract
Nanobubbles are defined as spherical gaseous objects in bulk liquid of diameter not exceeding 1000 nm. They display numerous interesting properties, including antibacterial and antimycotic effect. This promising characteristic can be utilised in disinfection. However, up to this point, the effect of nanodispersions on animal cell lines was not investigated. In this paper, nanodispersions of oxygen bubbles were generated using porous silicon carbide modules. Bubbles were characterised by Sauter diameter of 180 nm. Cytotoxicity of nanodispersions for mice cells from L929 line were investigated using MTT tests. Various medium concentrations diluted by either nanodispersion or distilled water were used. Results of tests showed the increase of metabolic activity of cells in samples diluted by nanodispersions compared to samples without nanodispersion addition.
Pages
51-58
Cite
Ulatowski, K., Sobieszuk, P., Kuźmińska, A., Ciach, T. (2018). INVESTIGATION OF CYTOTOXICITY OF OXYGEN NANOBUBBLE DISPERSIONS. Acta Sci. Pol. Biotechnol., 17(2), 51-58.
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