The experiments have been carried out with 7 dairy cows (of the lowland black-white race, 3-6 years old and body weights 490-580 kg) in two groups. The animals in experimental group [4 cows] and control group [3 cows] was in 1-2 days after calving. The uterus motility was recorded with balloon method by way of air transmission. After registration initial curve (30 min.) in cows the experimental group was intrauterine administrated 50 mg of beta – adrenergic blocker – propranolol (Uterotonic – Polfa) in 50 ml 0,9% NaCl and have been determined uterus contractions during 90 min. In this time was intravenous application of adrenaline (1 ml 0,1%). Similar investigations have been carried out also in second group (control), with has not received propranolol – intrauterine administrated only 50 ml 0,9% NaCl. It has been found that in cows of the experimental group after intrauterine infusion propranolol was improved motility of uterus – amplitude, frequency of contractions and tonus of myometrium increased. Any changes in control group were not observed.

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